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Sassafras Southern Bistro, Greenville, SC

Sassafras Southern Bistro

4.9
4.9
3491 Reviews
$30 and under
Southern

Make a reservation

2 people
9:30 PM
Booked 47 times today
  • Good for special occasions
  • Charming
  • Neighborhood gem
Located in the heart of downtown Greenville, South Carolina, Sassafras Southern Bistro serves an eclectic menu of American cuisine with a truly Southern influence. Menu items include steak, fresh seafood, salads, and amazing desserts. Sassafras Southern Bistro has a full bar featuring local beers on tap and an extensive wine selection both by the glass and by the bottle.



Start out your meal at Sassafras Southern Bistro with one of their amazing appetizers like the spicy pork tenderloin or the famous blue crab and pepper-jack nachos. Choose from entrees like the raved about shrimp and grits or the filet with house made pimento. Some vegetarian and gluten free options are available upon request.

Additional information

  • Dining style
    Casual Dining
  • Price
    $30 and under
  • Cuisines
    Southern, American
  • Hours of operation
    Mon–Thu 5:00 pm–9:00 pm Fri 5:00 pm–9:30 pm Sat 4:30 pm–9:30 pm
  • Phone number
    (864) 235-5670
  • Payment options
    AMEX, Discover, Mastercard, Visa
  • Dress code
    Casual Dress
  • Neighborhood
    Greenville
  • Cross street
    Main Street and Coffee Street
  • Parking details
    Parking is available in the Richardson Street parking garage that is conveniently located just a few steps away and is free to park on the weekends!
  • Public transit
    Parking garage is located at 66 Richardson Street. Once you park your car walk out of the parking garage and walk right into the open area. You will see Sassafras here, we have the green awning!
  • Additional
    Bar/Lounge, Beer, BYO Wine, Cocktails, Corkage Fee, Full Bar, Gluten-free Options, Happy Hour, Non-Smoking, Patio/Outdoor Dining, Patio/Outdoor Dining, Private Room, Wheelchair Access, Wine

What 3,491 people are saying

Overall ratings and reviews

Reviews can only be made by diners who have eaten at this restaurant

4.9
4.9 based on recent ratings
  • 4.8Food
  • 4.9Service
  • 4.8Ambience
  • 4.8Value

NoiseModerate

Loved For

  • South Carolina

    Best Service

  • South Carolina

    Best Value

  • South Carolina

    Southern

  • Greenville

    Best Overall

  • Greenville

    Best Food

  • Greenville

    Best Service

  • Greenville

    Best Ambiance

  • Greenville

    Best Value

  • Greenville

    Good for groups

  • Greenville

    Great for outdoor dining

Review summary

AI-generated from verified diner reviews
Sassafras Southern Bistro in Greenville shines with its "outstanding food and service." Guests praise the "charming atmosphere" and "generous portions." The menu's southern cuisine offers "delicious" dishes like shrimp and grits, and peanut butter pie. The "attentive staff" ensures a memorable dining experience. Consistently "great value," it's a local favorite.

3,491 Reviews
  1. Halm226

    Charleston4 reviews

    5.0

    Dined 2 days ago

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    Arrived early and was seated promptly. Our waitress was very knowledgeable and attentive but not overly. I ordered the salmon with lump crab and my wife had wasabi tuna. Also, we had the fried green tomatoes appetizer. The food was excellent topped off with free birthday dessert, peanut butter pie. The entire experience was an exceptional birthday celebration.

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  2. juliegb VIP

    Charleston31 reviews

    5.0

    Dined 3 days ago

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    Super service and good food. Thank you for a quick and enjoyable dinner before our concert tonight!

    Is this helpful?

  3. AaronJ

    Western KY3 reviews

    5.0

    Dined 5 days ago

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    This place was amazing! Excellent food at a very reasonable price. Service was top notch. If in Greenville this is a must try location.

    Is this helpful?

  4. Edward

    Charleston8 reviews

    5.0

    Dined 5 days ago

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    We're repeat customers, Sassafras is locally owned and very consistently managed. Great location, atmosphere, but especially attentive to quality food, service and also accommodating to allergies. The manager, Erin, came to me twice to confirm my allergy and ask approval of how they'd do the fish, here's how we'll sauté the spinach - super attention and results were excellent. Autumn, our server, was friendly and attentive while also moving along with other patrons in her busy evening. The owner was wandering through with his sharp eye. Dinner partners raved about the meatloaf, but for me the grilled seafood trio was the best ever. Very generous portions of food, and excellent appearance and taste, all for a reasonable price and very enjoyable experience!

    Is this helpful?

  5. Frank VIP

    St. Louis29 reviews

    5.0

    Dined 5 days ago

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    Excellent menu choices. Our choices (mango salmon, grilled shrimp, grilled brussel sprouts, sautéed asparagus) were all prepared very well.

    Is this helpful?

  6. Kirk VIP

    Charleston43 reviews

    5.0

    Dined 5 days ago

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    Everything about our experience at Sassafras was top notch. It was our guests first visit to Greenville and they were seriously impressed with Sassafras. Sally was terrific as our server! Meals were outstanding across the board!

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  7. OpenTable Diner

    Charleston3 reviews

    5.0

    Dined 6 days ago

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    Great service and amazing food like always. Friendly staff and looking forward to next time.

    Is this helpful?

  8. Linda VIP

    New York City9 reviews

    5.0

    Dined 6 days ago

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    Our server Sally was both knowledgeable and extremely friendly.

    Is this helpful?

  9. Champ VIP

    East Texas33 reviews

    5.0

    Dined 7 days ago

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    We eat here every trip to Greenville! Fab menu and really good healthy options! Lovely place!

    Is this helpful?

  10. LaurieE

    Philadelphia9 reviews

    5.0

    Dined on March 2, 2025

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    Great dinner (as always). One of our top dinner places

    Is this helpful?

FAQs

Sassafras Southern Bistro is rated 4.9 stars by 3491 OpenTable diners.

Yes, you can generally book this restaurant by choosing the date, time and party size on OpenTable.

Make a reservation

2 people
9:30 PM
Booked 47 times today
Google Map for Sassafras Southern Bistro

103 N Main St #107, Greenville, SC 29601

Additional information

  • Cross street
    Main Street and Coffee Street
  • Neighborhood
    Greenville
  • Hours of operation
    Mon–Thu 5:00 pm–9:00 pm Fri 5:00 pm–9:30 pm Sat 4:30 pm–9:30 pm
  • Price
    $30 and under
  • Cuisines
    Southern, American
  • Dining style
    Casual Dining
  • Dress code
    Casual Dress
  • Parking details
    Parking is available in the Richardson Street parking garage that is conveniently located just a few steps away and is free to park on the weekends!
  • Public transit
    Parking garage is located at 66 Richardson Street. Once you park your car walk out of the parking garage and walk right into the open area. You will see Sassafras here, we have the green awning!
  • Payment options
    AMEX, Discover, Mastercard, Visa
  • Additional
    Bar/Lounge, Beer, BYO Wine, Cocktails, Corkage Fee, Full Bar, Gluten-free Options, Happy Hour, Non-Smoking, Patio/Outdoor Dining, Patio/Outdoor Dining, Private Room, Wheelchair Access, Wine
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