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Best Neighborhood Gem Restaurants in Medical Center

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25 restaurants available nearby

A photo of Clementine restaurant
4.8
Exceptional(496)
Price: Very Expensive
• Contemporary American • North Central
Booked 20 times today
At Clementine, we’re serving seasonal, innovative eats in a modern & lively atmosphere. Our team, led by John (2023 James Beard nominee for Best Chef: Texas) and Elise Russ, draws inspiration from diverse global flavors. Our ever-evolving menu guarantees fresh and exciting options, while our dishes like the White Mushroom Salad, Ricotta Cavatelli and Clementine Crunch Bar remain cherished favorites. Our beverage menu is small but mighty, carefully curated to include only the most delicious wines & beers from our absolute favorite producers expertly selected to elevate your dining experience. Want your own bottle? Our corkage fee is $35 per 750ml.Our Dining Room provides comfortable indoor seating, while the Kitchen Bar boasts an exciting vantage point overlooking our open kitchen, allowing you to witness the creation of each dish. For a change of scenery, our covered patio, is perfect for al fresco dining, complete with heaters and blankets to keep you cozy on those cool nights.
A photo of Myron's at Alon Town Center restaurant
4.9
Exceptional(4661)
Price: Expensive
• Steak • North San Antonio
Booked 24 times today
Myron’s Prime Steak House is located in Alon Towne Centre at Northwest Military Highway and Wurzbach Parkway. We are open nightly serving Chicago prime beef, the top 2% of all prime beef in the U.S. A full bar and award winning wine list are available. Owner Bill Been, known to most for his 34 years of restaurant experience In San Antonio, has created a casual but elegant dining experience and invites you to come to Myron's, and enjoy!
A photo of Luce Ristorante E Enoteca restaurant
4.5
Awesome(1202)
Price: Moderate
• Italian • Medical Center
Founded in 2006, Luce is a local favorite featuring many traditional dishes. Flavors which often bring our guests back to their best memories of Italian specialties.My goal for this restaurant to create a warm environment for all guests that is typical of a true Italian heritage. Our menu consists of many Buonincontri family recipes and recipes brought back from travel to Italy. Fresh fish, meats and produce expound throughout Luce's offerings and a focus on the finest ingredients are what make Luce special. House made Gnocchi, Italian rice balls and homemade Mozzarella are just a few examples our passion for the finest Italian food.The word Enoteca means wine library. The walls of the entire restaurant are covered with wine bottles as you would expect books to cover the walls of a library. Wine is a very important part of an experience at Luce, with over 125 choices from our wine list available to you.
A photo of Perry's Steakhouse & Grille - San Antonio restaurant
4.7
Exceptional(9361)
Price: Expensive
• Steakhouse • La Cantera
Booked 138 times today
Located in La Cantera, Perry’s is a great place to spend an evening in The River City. Our popular Bar 79® presents floor-to-ceiling windows with an optional open-air lounge experience and expansive views overlooking local shops. Plus, the spacious, open design gives you the chance to catch glimpses of the chef as he crafts your favorite dishes — adding to the fresh, familiar atmosphere.
A photo of Signature restaurant
4.9
Exceptional(2618)
Price: Very Expensive
• American • La Cantera
Booked 33 times today
If you find yourself dreaming of the Texas Hill Country, savory comforts, spice, and the sultry depth of a fine Burgundy, you’ll be pleased to know about Signature at La Cantera Resort & Spa. The menu is straightforward and beguiling, featuring contemporary interpretations of classic dishes — fresher, brighter versions of traditional cuisine enlivened with unconventional Texas spirit. Gulf seafood conspires with Atlantic Coast oysters flown in fresh, and the Hill Country is well-represented year-round. Local and organic ingredients change the menu as the seasons peak and wane, but the constants are quality, flavor, artistry in the kitchen and a warm welcome when you walk in the door.
A photo of Supper restaurant
4.6
Exceptional(3176)
Price: Expensive
• Contemporary American • Downtown
Booked 67 times today
Supper is a neighborhood gem in downtown San Antonio, known for its unique, top-tier American cuisine and fantastic service. The ambiance is consistently praised, with reviewers noting the restaurant's 'cozy, restorative vibes', 'great atmosphere' and 'comfort, style and service'. The food is also highly rated, with dishes described as 'outstanding', 'amazing', and 'delicious'. It's a favorite among locals, and even visitors return time and again.
A photo of Chama Gaucha - San Antonio restaurant
4.9
Exceptional(6534)
Price: Very Expensive
• Brazilian Steakhouse • Stone Oak
Booked 184 times today
Welcome to Chama Gaucha Brazilian Steakhouse – where the ultimate dining experience awaits! Indulge your senses in a culinary journey like no other, as we offer an authentic taste of Brazil with our prime cut meats and unwavering commitment to superior service. Our expert gauchos skillfully carve an array of succulent, mouthwatering cuts right at your table, allowing you to savor the flavors and tenderness with every bite.But it's not just the extraordinary dishes that set us apart; it's the service that elevates your visit to unforgettable heights. Our attentive and knowledgeable staff are committed to ensuring that every moment of your dining experience is nothing short of exceptional.Whether you're celebrating a special occasion, enjoying a night out with friends, or simply seeking an extraordinary meal, Chama Gaucha promises to elevate your dining experience to new heights.
A photo of Eddie V’s – Wildfish – San Antonio restaurant
4.8
Exceptional(6655)
Price: Very Expensive
• Seafood • North San Antonio
Booked 91 times today
Eddie V's Prime Seafood is a luxury dining destination known for the seafood flown in from pristine waters around the world, as well as its premium hand-carved steaks. Dishes are artistically prepared and feature an ever-changing array of seasonal seafood, along with critically acclaimed prime center-cut steaks broiled to perfection. The restaurant's award-wining wine list, which has been recognized by Wine Spectator, has more than 300 wines curated by Eddie V's very own Advanced Sommelier. In the V Lounge, guests can sip classic creative cocktails and enjoy signature appetizers.
A photo of Paesanos - River Walk restaurant
4.5
Awesome(2229)
Price: Moderate
• Italian • Downtown
Booked 74 times today
Paesanos - River Walk is a beloved neighborhood gem. Reviewers consistently rave about its 'great food', 'excellent service' and 'wonderful atmosphere'. The 'beautiful setting outdoors at RiverWalk' and the 'relaxed environment' add to its charm. The restaurant is also praised for its 'authentic Italian cuisine' and 'large portions'. It's not just a dining spot, but a memorable experience!
A photo of Boiler House at Pearl restaurant
4.7
Exceptional(2104)
Price: Expensive
• Contemporary Southern • Downtown
Booked 31 times today
Boiler House at Pearl is a true Texas original. Situated in the historic Pearl Brewery complex on the San Antonio River Walk, this wine-centric restaurant occupies the former “boiler house” which powered the adjacent brewery. Lead by Executive Chef Alberto "Beto" Gutierrez, the menu focuses on grilled items from local farms and markets, with a focus on “Texas ranch-style” cuisine. These delicacies are paired with extraordinary wines from around the world (available by the glass, bottle and “to-go”), full bar, live music and a casual yet energetic atmosphere. The unique list of wines boasts some of the lowest prices in the area.The restaurant incorporates various private dining areas suitable for private or corporate functions and an expansive outdoor patio area where guests can enjoy dining alfresco. We can host groups anywhere from 9 up to 290 guests in our unique, flexible private event spaces.
‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

See what locals rave about

From verified diners like you
From verified diners like you
  • George
    San Antonio •15 reviews
    5.0
    Dined 1 day ago
    Food and wait staff were excellent. The service and food were amazing considering the number of people in this restaurant. It was full to capacity. Our water and tea glasses were refilled frequently. Our food was delivered quickly and hot. The food was very tasty. Nice experience. Kudos to both the wait and kitchen staff. Would definitely go back and recommend.
    More info
    Perry's Steakhouse & Grille - San AntonioPrice: Expensive• Steakhouse• La Cantera
    4.7
  • Rick
    Orange County •1 review
    5.0
    Dined 3 days ago
    December 24, 2024 We had the pleasure of dining at Myron’s on Christmas Eve, and I cannot say enough good things about this restaurant. From the moment we arrived, the experience was exceptional. The staff greeted us warmly and seated us promptly. Our waitress, Silvia, was fantastic—she greeted us right away and took our drink orders while we reviewed the menu. For dinner, we ordered a ribeye steak, green beans, and jalapeño mac and cheese. Every dish was absolutely delicious, but the steak stood out—it was easily one of the best I’ve had in a long time. If you’re looking for a place to enjoy a special dinner with your significant other, I highly recommend Myron’s at Alon Town Center. You won’t be disappointed!
    More info
    Myron's at Alon Town CenterPrice: Expensive• Steak• North San Antonio
    4.9
  • OpenTable DinerVIP
    San Antonio •6 reviews
    5.0
    Dined 5 days ago
    Truly the best meal we ever had. I’ve never had octopus like it and the best steak we’ve ever had. The service was spot on. We will be back.
    More info
    SignaturePrice: Very Expensive• American• La Cantera
    4.9
  • LeRoy
    San Antonio •59 reviews
    5.0
    Dined on Dec 20, 2024
    Another great meal at Clementine! Service was outstanding as well -- attentive but not intrusive, as well as very helpful with the menu. We (my wife and I) shared a beet salad and baked brie with truffle. She had their salmon and I had their Maine scallops. Great seafood prepared perfectly: moist and seared well, served with perfect complementary garnishes. We shared their Clementine crunch bar for dessert: just perfect as a light finish for our meal. Our cocktails were also delightful.
    More info
    ClementinePrice: Very Expensive• Contemporary American• North Central
    4.8
  • ElizabethVIP
    Austin •3 reviews
    5.0
    Dined on Dec 8, 2024
    Can’t say enough great things about this spot! Party of 10- they seated us immediately, food came fairly quickly even though there were several other large groups besides ours, everyone’s meal tasted delicious, portion size and taste were an incredible value (bonus- HH every day 5-7) plus they allowed separate checks!
    More info
    Luce Ristorante E EnotecaPrice: Moderate• Italian• Medical Center
    4.5
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