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Best Southwest American Restaurants in Medical District

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4 restaurants available nearby

A photo of Fearing's restaurant
4.7
Exceptional(6259)
Price: Very Expensive
• Southwest • Uptown
Booked 17 times today
Fearing's, nestled in the heart of Uptown Dallas, offers a quintessential American dining experience that is both authentic and innovative. Helmed by the legendary Dean Fearing, known as the "godfather of Modern Texas Cuisine," this restaurant is a beacon for lovers of bold American flavors with a Southwestern twist. Guests consistently rave about the impeccable service, with one review noting, "Food is exceptional, service is impeccable." From the famed tortilla soup to the exquisite chicken fried lobster, each dish is a testament to the rich culinary traditions of America. Experience "one of the best restaurants in Dallas" where great food and warm hospitality await.
A photo of Saint Ann Restaurant and Bar restaurant
4.6
Exceptional(2006)
Price: Moderate
• Southwest • Downtown
Booked 19 times today
Saint Ann Restaurant and Bar in the heart of Downtown Dallas is a standout destination for authentic Southwest cuisine. Revered for its "phenomenal" flavors and "wonderful dining experience," it’s an urban oasis that delights with both its ambiance and culinary offerings. Guests rave about the extensive menu that includes exquisite Southwest-inspired dishes, tastefully presented in a vibrant and unique setting. The restaurant's impressive garden patio is a perfect backdrop for enjoying a brunch, lunch, or dinner. With consistently "outstanding service" and a menu that caters to diverse dietary needs, Saint Ann offers an unforgettable taste of the Southwest.
A photo of Montage restaurant
4.3
Awesome(138)
Price: Expensive
• Southwest • Downtown
Booked 10 times today
Montage offers a truly remarkable Southwest dining experience, capturing the essence of Texas through its ranch-to-table menu crafted with locally sourced ingredients. Perched on the 11th floor of the JW Marriott Dallas Arts District Hotel, it provides diners with not only exquisite dishes but also breathtaking city views. Patrons rave about the "artful presentation" and "out of this world" taste of the food, emphasizing the authenticity and high quality of Southwest flavors. The service is consistently praised for being "friendly and attentive," making every visit special. Montage stands out as a must-visit destination for anyone seeking genuine Southwest cuisine in Dallas.
A photo of Two Mules Cantina at Texican Court restaurant
3.8
Excellent(25)
Price: Moderate
• Southwest • Irving
Experience the authentic Tex-Mex flavors of Texas at Two Mules Cantina, located within the Texican Court Hotel. Our menu, crafted by Executive Chef Marco Collins, offers a variety of Mexican-inspired dishes with a Texas flair. Unwind by the fire pits, roast s’mores, grab a margarita, and enjoy live music every Friday and Saturday night from 7–10 PM.
‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

See what locals rave about

From verified diners like you
From verified diners like you
  • charles
    San Diego •23 reviews
    5.0
    Dined today
    Everything and everyone was outstanding, food, service and atmosphere. Could not have asked for better lunch. My wife and I were celebrating her completion of cancer treatments and Zach and Charlie made it a perfect afternoon!
    More info
    Saint Ann Restaurant and BarPrice: Moderate• American• Downtown
    4.6
  • GinaVIP
    Phoenix / Arizona •13 reviews
    5.0
    Dined 3 days ago
    One of the best meals we have had out in a long time. The buffalo was exquisite, the scallops and wagu tartare amazing. The chef accommodated our request for seed-free oil dining and the bonus chocolates at the end were a nice treat. Highly recommend.
    More info
    Fearing'sPrice: Very Expensive• Southwest• Uptown
    4.7
  • Tim
    1 review
    5.0
    Dined 3 days ago
    The architecture and design (inside and outside) is stunningly beautiful - fabulous attention to detail and superbly executed / superbly maintained. Great wait staff, reasonable prices, solid cocktails, tacos, and apps. Nothing not to love for an upscale casual dining or drink experience, and plenty to appreciate.
    More info
    Two Mules Cantina at Texican CourtPrice: Moderate• Tex-Mex• Irving
    3.8
  • JoahVIP
    Dallas - Fort Worth •9 reviews
    5.0
    Dined on Feb 21, 2025
    Troy was amazing. He created custom cocktails to our liking, was prompt and incredibly hospitable. His recommendations were on point as well! Will definitely be back!
    More info
    MontagePrice: Expensive• Farm-to-table• Downtown
    4.3
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