Best Southern American Restaurants in Clayton

67 restaurants available nearby

A photo of The Capital Grille - St. Louis - Clayton restaurant

1. The Capital Grille - St. Louis - Clayton

4.8

Exceptional(2073)

Price: Very Expensive

• Southern american • Clayton

Booked 66 times today

The Capital Grille in Clayton, renowned for its exceptional Steakhouse cuisine, guarantees a memorable dining experience. Known for expertly prepared steaks that are dry-aged in-house for up to 24 days and meticulously hand-cut by their on-premise butcher, the quality is unparalleled. Diners rave about the flavor and tenderness of their steaks, with reviews highlighting the "outstanding experience" and "perfectly cooked steaks." The atmosphere is equally praised as "elegant and good for conversation," making it an ideal spot for any celebration. With over 350 wine selections perfectly complementing their succulent steaks, The Capital Grille stands out as a top dining destination in Clayton.

A photo of Oceano Bistro - Clayton restaurant

2. Oceano Bistro - Clayton

4.7

Exceptional(3630)

Price: Expensive

• Southern american • Clayton

Booked 16 times today

Nestled in the vibrant neighborhood of Clayton, Oceano Bistro offers a premier American dining experience with a focus on exquisite seafood that rivals coastal freshness. Patrons rave about their "perfectly cooked salmon" and the "amazing seared halibut with orzo," reflecting the bistro's commitment to quality and flavor. Reviewers consistently praise the "exceptional service" and the ambiance that makes every visit memorable. Oceano Bistro is celebrated for its ability to blend locally sourced ingredients with innovative dishes, earning accolades such as "always outstanding food and service!" and making it a beloved gem in St. Louis for an authentic American culinary journey.

A photo of Peel Wood Fired Pizza restaurant

3. Peel Wood Fired Pizza

4.5

Awesome(668)

Price: Moderate

• Southern american • Clayton

Booked 23 times today

Peel Wood Fired Pizza in Clayton is a gem for those craving authentic American cuisine with a unique twist. This chef-owned establishment takes pride in crafting dishes that are a cut above, using a wood-fired oven to infuse each pizza with a distinct, smoky flavor that patrons adore. Reviews often highlight not just the pizzas, but the variety of offerings, including the "amazing" Garlic Fired Chicken pizza and a seasonal favorite featuring maple and bacon, showcasing their commitment to creativity and quality. The atmosphere is described as both "fun" and "upscale," making it a perfect spot for any occasion. As one reviewer puts it, "the food was SO good and the ingredients were fresh!" making Peel Wood Fired Pizza a must-visit for delightful American dining.

4. Cafe La Vie

4.3

Awesome(208)

Price: Expensive

• Southern american • Clayton

Booked 7 times today

Cafe La Vie in Clayton, Saint Louis, is a sanctuary for those seeking authentic American cuisine with a touch of local St. Louis flair. Nestled inside the prestigious Le Meridien Hotel, this 7,400 sq. foot restaurant is renowned for its commitment to quality and authenticity. Patrons rave about the “best Brussels sprouts I have ever had” and the “perfectly cooked” beef tenderloin, highlighting the culinary prowess that Cafe La Vie brings to its dishes. With an inviting atmosphere described as "warm and inviting," it’s clear why guests feel special, whether they're celebrating Mother's Day or just stopping by after a long day. The glowing reviews consistently praise not just the food but the exceptional service, making Cafe La Vie a must-visit for a memorable dining experience in the heart of downtown Clayton.

A photo of Seven - Seven Gables Inn restaurant

5. Seven - Seven Gables Inn

4.0

Excellent(163)

Price: Moderate

• Southern american • Clayton

Immerse yourself in a welcoming ambiance where exceptional spirits and a delightful menu now align with the enduring tradition our guests cherish. Our Chef's unveil our latest lunch and dinner menus, along with the Clayton "Lost Classics"—a nostalgic selection resurrecting beloved dishes from historical Clayton area restaurants. Explore our revamped bar offerings, boasting a collection of over 50 whiskeys and wines, ensuring a delightful choice for every palate. Join us to relish the coziness of our enclosed Courtyard, featuring outdoor casual seating and inviting firepits.

6. Herbie's

4.4

Awesome(2398)

Price: Moderate

• Southern american • Clayton

Booked 47 times today

Herbie's in Clayton, St. Louis, stands out for its delightful blend of Asian cuisine, masterfully crafted by the innovative Chef Karl. Though Herbie's menu is inspired by multiple culinary traditions, its Asian dishes shine with authenticity and creativity. Guests rave about the unique flavors and high-quality ingredients, with one diner noting, "The food at Herbie's is amazing--so well prepared and presented." Another highlight is the restaurant's atmosphere, described as "elegant yet laid back," perfectly complementing an exquisite dining experience. Herbie's commitment to excellence is evident, making it a must-visit for anyone craving authentic Asian cuisine in St. Louis.

7. 801 Local

4.5

Awesome(1082)

Price: Expensive

• Southern american • Frontenac

Booked 57 times today

At 801 Local in Frontenac, breakfast isn't just the first meal of the day; it's a culinary celebration. Known for its "classy, comfortable and personable ambiance," this neighborhood gem serves up a breakfast that’s both eclectic and upscale. Patrons rave about the unique and delicious brunch offerings, highlighting the craft cocktails and the innovative dishes that make every morning feel like a special occasion. One diner exclaimed, "Brunch and craft cocktails [are] interesting and delicious!" ensuring a meal that goes beyond the ordinary. Whether it's a casual morning out or a significant celebration, 801 Local promises a breakfast experience that's crafted with care and served with pride, making every visit memorable.

8. Olive + Oak

4.8

Exceptional(1353)

Price: Expensive

• Southern american • St. Louis

Booked 97 times today

At Olive + Oak in St. Louis, the Fusion / Eclectic cuisine shines through a menu that balances innovation and comfort with a flair distinctly its own. Diners rave about the "creative dishes using the freshest ingredients," highlighting the restaurant's commitment to quality and culinary creativity. Described as a place where "food does not miss," Olive + Oak has crafted a dining experience that is both "unpretentious" and "top-flight." Whether it's celebrating a special occasion or enjoying a casual night out, guests are treated to "excellent eats" and "inventive" cocktails that make every visit memorable. With its vibrant atmosphere and attentive service, Olive + Oak stands out as a beacon of Fusion / Eclectic cuisine in St. Louis, making it a must-visit destination for both locals and visitors.

A photo of Maggiano's - St. Louis restaurant

9. Maggiano's - St. Louis

4.5

Awesome(5189)

Price: Moderate

• Southern american • Richmond Heights

Booked 171 times today

Maggiano's in St. Louis, located in Richmond Heights, is a treasure trove of Italian-American culinary excellence. Diners consistently praise the restaurant for its faultless service and delectable dishes that resonate with authentic American flair, offering an array of options that cater to every palate. As one reviewer enthuses, "I have NEVER tasted anything I didn't like!" from the seafood linguini to the exquisite crab cakes, each meal is a testament to quality and tradition. The atmosphere at Maggiano's is often highlighted as "perfect," making it an ideal spot for any occasion, from intimate dinners to family gatherings. With its commitment to impeccable service and a menu that sings with American cuisine classics, Maggiano's stands out as a top dining choice in St. Louis.

A photo of Truffles - St. Louis restaurant

10. Truffles - St. Louis

4.8

Exceptional(1386)

Price: Expensive

• Southern american • Clayton

Booked 22 times today

Truffles in Clayton, St. Louis, is a gem for those seeking the pinnacle of Contemporary American cuisine. Dubbed a "top-tier eatery" by STL Magazine, Truffles delights diners with its inventive approach to rustic and contemporary dishes. Specializing in house-made specialties like pasta and salumi, and sourcing locally raised meats and seafood, the restaurant ensures every plate embodies seasonality and freshness. Reviewers rave about their experiences, with one stating, "The food, service, and atmosphere were simply wonderful. Fine dining at its best." Whether it's the praised truffle frites or the sublime seasonal menus, Truffles consistently offers a culinary adventure that is both authentic and exceptional in the heart of St. Louis.

‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

Explore OpenTable

Clayton

Southern american

Best Southern American Restaurants in Clayton

Price

Regions

Neighborhoods

Top Rated

Dining Options

Seating Options

Accessibility

67 restaurants available nearby

1. The Capital Grille - St. Louis - Clayton

2. Oceano Bistro - Clayton

3. Peel Wood Fired Pizza

4. Cafe La Vie

5. Seven - Seven Gables Inn

6. Herbie's

7. 801 Local

8. Olive + Oak

9. Maggiano's - St. Louis

10. Truffles - St. Louis

Explore OpenTable