Enable JavaScript to run this app.
Skip to main content
OpenTable logo
  1. Home
  2. United States
  3. San Antonio

Best Southwest American Restaurants in San Antonio

Price
Regions
Neighborhoods
Top Rated
Dining Options
Seating Options
Accessibility

69 restaurants available nearby

A photo of Supper restaurant
1. Supper
4.6
Exceptional(3167)
Price: Expensive
• Mexican • Downtown
Booked 30 times today
Supper, nestled in the heart of Downtown San Antonio, offers an exceptional Contemporary American dining experience that embodies the essence of South Texas hospitality. Housed in the historic and charming Hotel Emma, Supper is celebrated for its "phenomenal food service and ambiance." Diners rave about the "inventive seasonal cocktails" and the meticulously crafted dishes such as the "country fried quail" and "mushroom risotto," which are consistently lauded as "out of this world." The restaurant's commitment to quality is evident, with one guest noting, "the food and service were beyond phenomenal!" Whether it's a special occasion or a casual meal, Supper's vibrant atmosphere and culinary excellence make it a standout destination for Contemporary American cuisine.
A photo of Domingo Restaurante restaurant
2. Domingo Restaurante
4.5
Awesome(785)
Price: Expensive
• Mexican • Downtown
Booked 100 times today
Join us in our open-air restaurant on the Historic San Antonio River Walk with a natural ambiance where curated contemporary art intersects with a historical setting. Domingo's menus offer the flavors of South Texas and an agave-forward beverage program celebrating the culture of San Antonio with modern culinary flair.
A photo of Southerleigh Fine Food & Brewery restaurant
3. Southerleigh Fine Food & Brewery
4.8
Exceptional(3102)
Price: Moderate
• Mexican • Downtown
Booked 52 times today
Southerleigh Fine Food & Brewery in downtown San Antonio masterfully celebrates Southern cuisine with a modern twist. Helmed by Chef Jeff Balfour, whose Galveston roots shine through in dishes like the "BEST shrimp boil entree in town!" and the mouth-watering crab mac and cheese, which has been called "the bomb." Diners rave about the "excellent service" and "fun environment," with specialties such as the jalapeño cornbread and crispy, juicy fried chicken consistently earning high praise. Located in the historic Pearl brewhouse, Southerleigh not only offers a delectable menu but also brews its own beer, providing a uniquely Southern experience that is both innovative and deeply rooted in tradition.
A photo of Chart House Restaurant - Tower of the Americas restaurant
4. Chart House Restaurant - Tower of the Americas
4.5
Awesome(16572)
Price: Moderate
• Mexican • Downtown
Booked 120 times today
Dine in the heart of Downtown San Antonio at Chart House Restaurant, a haven of American cuisine that promises more than just a meal. Celebrated for both its culinary prowess and enchanting views, Chart House offers an array of finely-crafted American dishes, from fresh fish specialties to the sumptuous slow-roasted prime rib. Guests rave about the "delicious food and great service," with highlights including the "best key lime pie ever" and an original Hot Chocolate Lava Cake that perfectly concludes a memorable dining experience. Whether it's the stunning city vistas or the "exceptional service," Chart House provides a dining experience that consistently delights and surprises, making it a must-visit for locals and tourists alike.
A photo of Bohanan's Prime Steaks and Seafood restaurant
5. Bohanan's Prime Steaks and Seafood
4.8
Exceptional(8260)
Price: Very Expensive
• Mexican • Downtown
Booked 35 times today
Bohanan's Prime Steaks and Seafood in downtown San Antonio is a gastronomic landmark where the allure of tender, prime beef and fresh seafood create a perfect dining experience. Known for its mesquite-grilled steaks like the "spectacular" Akaushi beef, Bohanan’s also boasts a AAA Four Diamond rating and a Wine Spectator’s Best of Award of Excellence. Diners rave about the "perfect steak doneness" and "spectacular table-side desserts flambé." The ambiance, set in a historic building near the River Walk, adds to its charm, making every visit memorable. It’s no wonder guests say, "Bohanan’s is consistently the best service in the city," making it a must-visit for anyone seeking the quintessential steakhouse experience.
A photo of Mezquite restaurant
6. Mezquite
4.5
Awesome(197)
Price: Moderate
• Mexican • Downtown
Booked 42 times today
Nestled in the heart of Downtown San Antonio, Mezquite is a culinary gem that brings the vibrant flavors of the Sonoran region to life. Diners rave about the authenticity and quality of the cuisine, with one guest exclaiming, "The food and everything was beyond great!! Can’t wait to come back! Congratulations!" From the grilled meats and house-made flour tortillas to the exquisite cocktails, each dish is a celebration of tradition with a modern twist. The ambiance, whether on mariachi nights or a regular evening, enhances the dining experience, making every visit memorable. Whether it's the "life-changing" Elotes or the "divine" Carne Asada quesadilla, Mezquite stands out as a top destination for Mexican/Southwestern cuisine in San Antonio.
A photo of Isidore restaurant
7. Isidore
4.6
Exceptional(88)
Price: Very Expensive
• Mexican • Downtown
Booked 13 times today
Nestled in the heart of Downtown San Antonio, Isidore is a culinary gem renowned for its exquisite fine cuts and vibrant atmosphere. Patrons rave about the "perfectly prepared" shareable ribeye and the "beyond fantastic" Wagyu Ribeye, which comes with uniquely sauced potatoes that are a must-try. The authenticity and mastery of fine cuts at Isidore are evident, with one diner describing their experience as "probably the best restaurant in San Antonio." The intimate décor and robust wine list complement the high-quality meats, making Isidore the ideal spot for a celebration or a luxurious night out. Join the chorus of delighted guests and indulge in a fine cuts cuisine that truly stands out at Isidore.
A photo of Boiler House at Pearl restaurant
8. Boiler House at Pearl
4.7
Exceptional(2104)
Price: Expensive
• Mexican • Downtown
Booked 9 times today
Nestled in the historic Pearl Brewery complex in Downtown San Antonio, Boiler House at Pearl stands as a beacon of exceptional Steakhouse cuisine. With a focus on "Texas ranch-style" dishes, Executive Chef Alberto "Beto" Gutierrez masterfully crafts grilled specialties using only the finest ingredients sourced from local farms. Patrons rave about the perfection of their steaks, with one guest exclaiming, "One of the best steaks I have had!" Complemented by a vibrant atmosphere and a meticulously curated wine list offered at unbeatable prices, the Boiler House promises not only a meal but an experience. As an added bonus, the outdoor patio provides a perfect backdrop for al fresco dining along the scenic River Walk, making it a must-visit destination for both locals and visitors.
A photo of Brenner's on the River Walk restaurant
9. Brenner's on the River Walk
4.7
Exceptional(313)
Price: Moderate
• Mexican • Downtown
Booked 31 times today
Brenner's on the River Walk in downtown San Antonio offers a quintessential American dining experience, combining tradition and elegance with a stunning three-story dining room overlooking the river. A continuation of the Brenner's legacy since 1936, this restaurant excels in crafting classic American dishes, especially its steaks which are often described as "cooked to perfection" and are a highlight among diners. Reviewers rave about the "amazing food amazing atmosphere" and the personalized service that makes each visit memorable. One guest mentioned, "The steak was flavorful and cooked to perfection," underscoring the restaurant's commitment to quality. Whether it's for a casual dinner or a special occasion, Brenner’s on the River Walk is celebrated for its exceptional American cuisine and vibrant ambiance, making it a must-visit culinary destination in San Antonio.
A photo of Ida Claire - San Antonio restaurant
10. Ida Claire - San Antonio
4.6
Exceptional(2488)
Price: Moderate
• Mexican • Alamo Heights
Booked 48 times today
Ida Claire in Alamo Heights, San Antonio, is a treasure trove for breakfast enthusiasts, blending Southern charm with a twist on traditional dishes. Known for its "notched up southern" cuisine, the restaurant offers an exciting breakfast menu, including must-try chicken and waffles and delightful biscuits served with various accompaniments. The authenticity and quality of the breakfast at Ida Claire shine through in customer reviews, with diners celebrating the "amazing food" and "excellent service." One standout review raves about the "cinnamon pull apart on weekend brunch," highlighting the unique and flavorful offerings that keep guests returning. Whether it's the engaging atmosphere or the innovative southern dishes, Ida Claire provides a memorable breakfast experience that is both authentic and high quality.
‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

See what locals rave about

From verified diners like you
From verified diners like you

Explore OpenTable

Discover
OpenTable
  • About Us
  • Blog
  • Careers
  • Press
More
Our sites
Businesses
  • Delight more diners
Join us on
  • Privacy Policy
  • Terms of Use
  • Cookies and Interest-Based Ads
  • Cookie Preferences
Copyright © 2024 OpenTable, Inc. 1 Montgomery St Ste 500, San Francisco CA 94104 - All rights reserved.
OpenTable is part of Booking Holdings, the world leader in online travel and related services.
Booking Logo
Priceline Logo
KAYAK Logo
Agoda Logo
OpenTable Logo