Best Southwest American Restaurants in W. University / Med Center

183 restaurants available nearby

A photo of Drake's Hollywood - Houston restaurant

1. Drake's Hollywood - Houston

4.5

Price: Very Expensive

• Mexican • Montrose

Booked 55 times today

Drake's Hollywood in Montrose, Houston, is a haven for steak aficionados, offering an experience that is as authentic as it is exceptional. Known for its “amazing” dry-aged Delmonico steaks, the restaurant consistently receives rave reviews for both its culinary offerings and vibrant ambiance. Diners frequently highlight the “mouth-watering” quality of the steaks, with one reviewer declaring it as “the best steak” they've ever tasted. Each steak is perfectly prepared, capturing the essence of Old Hollywood glamour with every bite. The impeccable service and lively atmosphere only enhance the dining experience, making it a must-visit destination for steak lovers.

2. Rosie Cannonball

4.7

Exceptional(46)

Price: Expensive

• Mexican • Montrose

Booked 49 times today

Rosie Cannonball in Montrose, Houston, is a vibrant celebration of authentic Italian cuisine, skillfully prepared with a focus on live fire cooking. The restaurant's wood-burning oven and grill bring out the best in their hand-crafted pastas and wood-fired pizzas, drawing rave reviews for their "perfection" and "top quality." The menu, inspired by fresh, local ingredients, pairs exquisitely with an Italian-centric wine list curated by Master Sommelier June Rodil. Diners consistently praise the "extraordinary" service and "exceptional" food, making it a beloved gem in the heart of Houston. With its lively atmosphere and delectable offerings, Rosie Cannonball promises an unforgettable Italian dining experience.

3. Milton's

4.7

Exceptional(84)

Price: Expensive

• Mexican • Rice Village

Booked 50 times today

Milton's is a delightful culinary gem nestled in the heart of Rice Village, Houston, offering an exceptional blend of American and Italian-American cuisine that truly stands out. Known for "delicious food and perfect service," Milton's is celebrated for its homemade pastas, like the unforgettable mushroom pasta, and wood-fired meats that offer a comforting yet innovative dining experience. Guests rave about the "outstanding service and food quality," making it a must-visit for those seeking authentic American flavors with a twist. The vibrant atmosphere and impeccable service ensure that every visit is memorable, promising patrons a taste of true American dining excellence.

4. Eunice

4.7

Exceptional(2618)

Price: Moderate

• Mexican • Upper Kirby / Shepherd Corridor

Booked 51 times today

Eunice, nestled in the vibrant Upper Kirby area of Houston, is a seafood lover's paradise, offering a tantalizing menu inspired by the rich flavors of South Louisiana. The restaurant's seafood dishes, such as the "best gumbo I ever had" and the "outstanding oysters," are frequently praised for their authenticity and quality, transporting diners straight to the Gulf Coast. Executive Chef Drake Leonards masterfully infuses European influences with local ingredients, creating a unique culinary experience that keeps guests coming back for more. The warm, inviting atmosphere and exceptional service make Eunice an unforgettable dining destination for seafood enthusiasts.

A photo of Clark's Oyster Bar - Houston restaurant

5. Clark's Oyster Bar - Houston

4.8

Exceptional(415)

Price: Expensive

• Mexican • Montrose

Booked 38 times today

Clark's Oyster Bar in Montrose, Houston, is a shining gem of Contemporary American cuisine, delighting diners with its exquisite blend of fresh seafood and classic American dishes. This vibrant restaurant is renowned for its "amazing oysters and seafood," bringing flavors from places like Maine and the Pacific Northwest to the heart of Houston. Diners rave about the "delicious variety of oysters" and the "best cioppino ever," making it a must-visit for seafood aficionados. The light, airy ambiance, complete with a charming outdoor patio, offers a perfect setting to enjoy a "wonderful experience" with "great food and service." Whether you're savoring a classic lobster roll or indulging in a luscious key lime tart, Clark's promises an authentic and memorable Contemporary American dining experience.

6. Balboa Surf Club

4.8

Exceptional(63)

Price: Expensive

• Mexican • Galleria / Uptown

Booked 59 times today

Balboa Surf Club in the vibrant Uptown Houston area is a must-visit for seafood lovers. The restaurant is renowned for its exquisitely fresh seafood, with diners raving about the "best seafood I've ever had in Houston!" Guests are consistently impressed by the quality and creativity of the offerings, like the "mind-blowing creative" sushi rolls and the "HUGE crab cake" packed with flavor. The Miso Salmon is frequently highlighted as "some of the best tasting salmon," while the King Crab hand roll is hailed as "the best bite in Houston." Balboa Surf Club promises a culinary experience where freshness and authenticity shine through every dish.

7. Leo's River Oaks

4.5

Awesome(93)

Price: Very Expensive

• Mexican • River Oaks

Booked 40 times today

Leo's River Oaks in Houston is a shining star of Contemporary American cuisine, offering an exquisite dining experience that's hard to match. Guests rave about the "amazing food and cocktails," with standout dishes like the King Salmon and deviled egg trio leaving a lasting impression. The restaurant's elegant decor and live piano music provide a sophisticated atmosphere, perfect for special occasions or a memorable night out. Diners frequently mention the "outstanding service," highlighting the attentive and knowledgeable staff who enhance the dining experience. Leo's River Oaks is truly a "must-try" for anyone seeking exceptional Contemporary American dining in River Oaks.

A photo of Hudson House - River Oaks restaurant

8. Hudson House - River Oaks

4.7

Exceptional(423)

Price: Moderate

• Mexican • River Oaks

Booked 66 times today

Hudson House - River Oaks is a seafood lover's paradise, bringing the authentic flavors of the East Coast to Houston with a flair for freshness and quality. The oysters, "flown in daily," are a testament to their commitment to providing only the best, and pair perfectly with their renowned "World’s Coldest Martinis." The reviews speak volumes, with diners raving about the "superb" raw oysters and the "best grilled redfish" they've ever had in Houston. The restaurant’s dedication to serving consistently delicious seafood makes it a standout choice for anyone craving an unforgettable seafood dining experience.

9. Flora

4.7

Exceptional(800)

Price: Moderate

• Mexican • Montrose

Booked 50 times today

Flora, nestled in the vibrant Montrose neighborhood of Houston, shines as a beacon for cocktail enthusiasts. This exquisite cocktail bar is celebrated for its "stunning brass and marble bar," which provides a dazzling backdrop to the expertly crafted drinks. The selection of tequila and mezcal is unparalleled, promising an authentic taste of Mexico with a Texas twist. Diners rave about the "amazing food and drinks," highlighting the bar's ability to complement its flavorful dishes with equally impressive cocktails. Flora's commitment to quality and innovation makes it a must-visit for those seeking a memorable cocktail experience in a "beautiful and lively" setting.

10. JOEY Uptown

4.6

Exceptional(105)

Price: Moderate

• Mexican • Westside

Booked 121 times today

JOEY Uptown in Westside, Houston, offers an exceptional dining experience with its Global, International cuisine. With a team of celebrated Executive Chefs, this restaurant delivers a "scrumptious" and "perfectly crafted" menu that has patrons raving about its diverse and flavorful dishes. The open concept dining room and temperature-controlled patio create a lively and inviting atmosphere, accented by art from local talents. Guests consistently praise the "fantastic food, excellent service, and great vibe," making JOEY Uptown a must-visit for anyone seeking a unique and memorable culinary adventure. Whether for a special occasion or a casual night out, this spot is sure to impress.

‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

See what locals rave about

From verified diners like you

A
Alan
Kansas City / Kansas •12 reviews
5.0
Dined 2 days ago
Return trip to share Picos with my wife. We shared a pork shank that was fabulous and finished with churros served warm with dipping sauces. What a great evening.
More info
Arnaldo Richards' PicosPrice: Expensive• Regional Mexican• Upper Kirby / Shepherd Corridor
•
4.8
A
ArmandoVIP
Houston •5 reviews
5.0
Dined 6 days ago
Great service to make a fun time for family and friends
More info
Escalante's Fine Tex-Mex & Tequila - Town & CountryPrice: Moderate• Tex-Mex• Westside
•
4.6
OT
OpenTable Diner
Houston •1 review
5.0
Dined 6 days ago
Irma’s is a great downtown restaurant. We ate there before a Rockets game as it is easily walkable to Toyota Center or Minute Maid Park for that matter. The service was stellar, the food delicious and the atmosphere inviting. Will definitely go back when our activities take us downtown.
More info
Irma's SouthwestPrice: Expensive• Mexican / Southwestern• Downtown
•
4.8
A
Anissa
Houston •3 reviews
5.0
Dined on Dec 20, 2024
Had team Christmas luncheon there. We had a great time
More info
Escalante's Fine Tex-Mex & Tequila - MeyerlandPrice: Moderate• Tex-Mex• Bellaire
•
4.6
A
Arsheen
Houston •1 review
5.0
Dined on Dec 6, 2024
The food was excellent, and the restaurant provides a quiet and pleasant atmosphere, making it a great spot to catch up with friends.
More info
Escalante's Fine Tex-Mex & Tequila - Highland VillagePrice: Moderate• Tex-Mex• River Oaks
•
4.8

Best Southwest American Restaurants in W. University / Med Center

Price

Regions

Neighborhoods

Top Rated

Dining Options

Seating Options

Award-winning

Accessibility

183 restaurants available nearby

1. Drake's Hollywood - Houston

2. Rosie Cannonball

3. Milton's

4. Eunice

5. Clark's Oyster Bar - Houston

6. Balboa Surf Club

7. Leo's River Oaks

8. Hudson House - River Oaks

9. Flora

10. JOEY Uptown

See what locals rave about

Explore OpenTable