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Best Contemporary American Restaurants in Medical Center

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29 restaurants available nearby

A photo of Clementine restaurant
4.8
Exceptional(479)
Price: Very Expensive
• Contemporary american • North Central
Booked 11 times today
At Clementine, we’re serving seasonal, innovative eats in a modern & lively atmosphere. Our team, led by John (2023 James Beard nominee for Best Chef: Texas) and Elise Russ, draws inspiration from diverse global flavors. Our ever-evolving menu guarantees fresh and exciting options, while our dishes like the White Mushroom Salad, Ricotta Cavatelli and Clementine Crunch Bar remain cherished favorites. Our beverage menu is small but mighty, carefully curated to include only the most delicious wines & beers from our absolute favorite producers expertly selected to elevate your dining experience. Want your own bottle? Our corkage fee is $35 per 750ml.Our Dining Room provides comfortable indoor seating, while the Kitchen Bar boasts an exciting vantage point overlooking our open kitchen, allowing you to witness the creation of each dish. For a change of scenery, our covered patio, is perfect for al fresco dining, complete with heaters and blankets to keep you cozy on those cool nights.
A photo of Kona Grill - North Star restaurant
4.2
Awesome(581)
Price: Moderate
• Contemporary american • North San Antonio
Booked 9 times today
Kona Grill at North Star Mall in North San Antonio is an exemplary destination for authentic American cuisine, combining classic grill favorites with a unique twist. This restaurant stands out for its "global menu of contemporary American favorites, award-winning sushi, and specialty craft cocktails in a polished, casual atmosphere" that patrons adore. The quality of their steak is often praised as "Absolutely the best steak in Texas!" along with their exceptional service, making it a go-to spot for both locals and visitors. Reviewers consistently highlight the staff's attentiveness and the vibrant atmosphere, making every dining experience memorable. Whether it's for a hearty brunch, a delightful dinner, or a lively happy hour, Kona Grill at North Star offers a perfect blend of quality, service, and American cuisine flair.
A photo of Supper restaurant
4.5
Awesome(3154)
Price: Expensive
• Contemporary american • Downtown
Booked 32 times today
Supper, nestled in the heart of Downtown San Antonio, offers an exceptional Contemporary American dining experience that embodies the essence of South Texas hospitality. Housed in the historic and charming Hotel Emma, Supper is celebrated for its "phenomenal food service and ambiance." Diners rave about the "inventive seasonal cocktails" and the meticulously crafted dishes such as the "country fried quail" and "mushroom risotto," which are consistently lauded as "out of this world." The restaurant's commitment to quality is evident, with one guest noting, "the food and service were beyond phenomenal!" Whether it's a special occasion or a casual meal, Supper's vibrant atmosphere and culinary excellence make it a standout destination for Contemporary American cuisine.
A photo of Ida Claire - San Antonio restaurant
4.6
Exceptional(2465)
Price: Moderate
• Contemporary american • Alamo Heights
Booked 97 times today
Ida Claire in Alamo Heights, San Antonio, is a treasure trove for breakfast enthusiasts, blending Southern charm with a twist on traditional dishes. Known for its "notched up southern" cuisine, the restaurant offers an exciting breakfast menu, including must-try chicken and waffles and delightful biscuits served with various accompaniments. The authenticity and quality of the breakfast at Ida Claire shine through in customer reviews, with diners celebrating the "amazing food" and "excellent service." One standout review raves about the "cinnamon pull apart on weekend brunch," highlighting the unique and flavorful offerings that keep guests returning. Whether it's the engaging atmosphere or the innovative southern dishes, Ida Claire provides a memorable breakfast experience that is both authentic and high quality.
A photo of Bliss Restaurant restaurant
4.9
Exceptional(4968)
Price: Very Expensive
• Contemporary american • Downtown
Booked 24 times today
Bliss is consistently among San Antonio’s best restaurants in terms of quality, service and atmosphere. Bliss is located just blocks away from downtown San Antonio in the burgeoning Southtown area. Our mission is to express excellence in the most inclusive, genuine and hospitable way. Bliss serves contemporary American cuisine. Our menu changes frequently with an emphasis on what is seasonal and creative over what is predictable and familiar. Our goal is to create a relaxed yet elegant dining experience in a genuine and comfortable environment.
A photo of Restaurant Claudine restaurant
4.6
Exceptional(557)
Price: Moderate
• Contemporary american • Downtown
Booked 15 times today
At Restaurant Claudine in downtown San Antonio, Southern cuisine is elevated with a touch of French flair, creating an unforgettable dining experience. Nestled in the up-and-coming Government Hill neighborhood, this establishment features "grandma's southern-comfort style cuisine" with sophisticated twists, such as fried chicken with fermented hot honey and pomme puree. Praised for its "charming" atmosphere and "exquisite" food, diners rave about the "delicious and delightful" dishes like cornbread, beignets, and fried chicken. As one reviewer exclaimed, "Everything about this place is amazing!" ensuring that Restaurant Claudine is a must-visit for those seeking authentic Southern cuisine with an elegant touch.
A photo of Ambler - Texas Kitchen + Cocktails restaurant
4.3
Awesome(539)
Price: Moderate
• Contemporary american • Downtown
Booked 9 times today
Ambler - Texas Kitchen + Cocktails, nestled in the heart of Downtown San Antonio, is a haven for Comfort Food lovers seeking authenticity and robust Texas flavors. Situated on the scenic Riverwalk, Ambler celebrates the state's rich cattle ranching history with a menu that's as bold and inviting as Texas itself. From the "flavorful and cooked to perfection" Fried Chicken Dinner and Salmon to the "best pork chop I’ve ever had," guests consistently praise the quality and heartiness of the meals. Coupled with its vibrant environment and exceptional service, Ambler ensures a memorable dining experience. As one diner put it, "The steak is amazing! The service is first class," making it a must-visit for anyone craving genuine Texas Comfort Food.
A photo of Sweetfire Kitchen - La Cantera Resort and Spa restaurant
4.7
Exceptional(676)
Price: Moderate
• Contemporary american • La Cantera
Booked 4 times today
Sweet Fire Kitchen, located on the lobby level of the La Cantera Resort & Spa, features an open-air exhibition style kitchen with a wood fired pizza oven. Guests will enjoy a twist on regional, home-style cuisine along with signature dishes from our fire-roasted oven. The casual dining venue offers indoor seating with spectacular views of the Texas Hill Country and al fresco dining overlooking Plaza San Saba. Whether you're craving an unexpected take on deviled eggs or a classic wood-fired pizza, SweetFire Kitchen guests can have it all. The restaurant also offers a full-service bar with unique craft cocktails, an extensive wine list and draught beers.SFK is happy to announce our place as a 2024 Open Table Diner's Choice Award Winner.
A photo of Qulturé restaurant
4.4
Awesome(29)
Price: Expensive
• Contemporary american • Stone Oak
Booked 5 times today
Qulturé offers a sublime experience of Contemporary American cuisine, blending Southern-inspired flavors with a modern twist in the upscale Stone Oak neighborhood of San Antonio. Patrons rave about the exceptional quality of dishes like the oxtail sandwich and stuffed salmon, frequently highlighting Chef Jordan's culinary prowess. "The food is absolutely amazing!! Chef Jordan did an experiment job," one review enthuses, showcasing the chef's skill in delivering consistently flavorful and well-seasoned dishes. The lively atmosphere and sophisticated setting further enhance the dining experience, making Qulturé a must-visit for anyone seeking the best in Contemporary American dining with a vibrant, energetic twist.
A photo of Kona Grill - San Antonio restaurant
3.9
Excellent(1142)
Price: Moderate
• Contemporary american • La Cantera
Booked 19 times today
Kona Grill in San Antonio, nestled in the vibrant Shops at La Cantera, is a gem for lovers of Contemporary American cuisine. With its "global menu of contemporary American favorites," Kona Grill excels in delivering a polished, casual dining experience. Patrons rave about the quality and variety, highlighting dishes like the surf & turf and sea bass sliders as "bomb" choices. The restaurant's dedication to fresh, well-prepared dishes shines through in reviews, with guests consistently praising the "fantastic" food and atmosphere. Happy Hour and weekend brunch are particularly noted, offering great value in a welcoming setting. Whether you're in for sushi that is "always fresh and delicious" or craft cocktails that elevate your meal, Kona Grill stands out as a must-visit for an authentic taste of Contemporary American cuisine in San Antonio.
‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

See what locals rave about

From verified diners like you
From verified diners like you
  • Alicia
    San Diego •8 reviews
    5.0
    Dined 2 days ago
    What an amazing Thanksgiving feast! We thought we’d be choosing 1 starter, 1 entree & 2 sides from the Ambler Thanksgiving menu, but know, we were served EVERYTHING ON THE MENU. Our server, Francisco, was extremely attentive & obviously a very professional experienced waiter, we wanted for nothing and thoroughly enjoyed and appreciated the great food, ambiance & service!
    More info
    Ambler - Texas Kitchen + CocktailsPrice: Moderate• Contemporary American• Downtown
    4.3
  • Cheryl
    San Antonio •4 reviews
    5.0
    Dined 2 days ago
    Our server, Paul, was sooo charming and full of the history of the hotel. He made our Thanksgiving dinner very special. Never met such a smooth and respectful waiter!! We left happy bc of him & the delicious cuisine!
    More info
    SupperPrice: Expensive• Contemporary American• Downtown
    4.5
  • Meic
    San Antonio •1 review
    5.0
    Dined 3 days ago
    It was a wonderful experience, I chose Claudine to celebrate my daughter's 14th birthday, at first it was due to the style of decoration and ambiance there, which is exactly what my daughter loves and I wanted to provide her with this experience. But when we got there everything was above our expectations, the perfect service, the food delicious and very well served.
    More info
    Restaurant ClaudinePrice: Moderate• Contemporary American• Downtown
    4.6
  • Brenda
    San Antonio •3 reviews
    5.0
    Dined 7 days ago
    Our first time to Bliss was wonderful. Nick was our waiter and he did not disappoint. He shared the history of the building and the restaurant. His knowledge of the menu and sense of humor provided both me and my husband a wonderful and memorable evening. I would recommend Bliss to anyone looking for an intimate dinner with unique and delicious food.
    More info
    Bliss RestaurantPrice: Very Expensive• Contemporary American• Downtown
    4.9
  • Veronica
    San Antonio •1 review
    5.0
    Dined 7 days ago
    Clementine never disappoints with their special event afternoon tea. Food was amazing, desserts exquisite.
    More info
    ClementinePrice: Very Expensive• Contemporary American• North Central
    4.8
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