Enable JavaScript to run this app.
Skip to main content
OpenTable logo
  1. Home
  2. United States
  3. San Diego

Best American Restaurants in Mission Hills

Price
Regions
Neighborhoods
Top Rated
Dining Options
Seating Options
Award-winning
Accessibility

136 restaurants available nearby

A photo of Old Town Tequila Factory Restaurant & Cantina restaurant
3.7
Very Good(1144)
Price: Moderate
• American • Old Town
Booked 21 times today
Nestled in the historic heart of Old Town, San Diego, Old Town Tequila Factory Restaurant & Cantina offers a spectacular blend of contemporary Mexican cuisine and panoramic views. Praised for its "stellar taco bar" and "delicious authentic Mexican food," this charming rooftop venue serves dishes crafted from "old world recipes" that promise authenticity and flavor. Guests rave about the "fantastic food and drinks" and highlight the ambiance, with one noting the experience as "like the ultimate beach vacation." Whether it's enjoying a Sunday Champagne brunch or a sunset dinner, the Old Town Tequila Factory provides a vibrant setting perfect for any gathering, complemented by attentive service and "the best happy hour deals." This spot is a must-visit for those seeking a genuine taste of contemporary Mexican cuisine in a picturesque setting.
A photo of Casa De Freds, Tacos y Tequila restaurant
4.5
Awesome(320)
Price: Moderate
• American • Old Town
Booked 38 times today
Nestled in the heart of Old Town, San Diego, Casa de Freds, Tacos y Tequila offers a vibrant slice of Tex-Mex heaven. Since 2001, this festive spot has been a favorite for both locals and visitors, praised for its "amazing" molcajete and "best burritos in town!" The authentic Baja-infused menu shines with high-quality ingredients that bring out the bold and savory flavors typical of Tex-Mex cuisine. Diners rave about the "outstanding" tacos and the freshness of the margaritas, making it a must-visit for anyone seeking a genuine taste of Tex-Mex in San Diego. With a dog-friendly patio and a festive atmosphere, Casa de Freds is the perfect spot to enjoy great food and great times.
A photo of Herb & Wood restaurant
4.7
Exceptional(6474)
Price: Expensive
• American • Little Italy
Booked 39 times today
Herb & Wood in Little Italy, San Diego, epitomizes the essence of Mediterranean cuisine with a delightful twist of Californian flair. Celebrated Chef Brian Malarkey crafts a menu that transforms simple ingredients into a symphony of flavors, all centered around a wood-fired concept that accentuates each dish's rustic, authentic taste. Reviewers consistently praise the restaurant's vibrant atmosphere and innovative dishes, with one guest exclaiming, "The bone marrow and oyster dish was especially impressive!" and another noting the "swordfish was very fresh and tasty." Herb & Wood not only offers a feast for the taste buds but also a Mediterranean dining experience that is both heartfelt and memorable, making it a culinary jewel in San Diego.
A photo of Ironside Fish & Oyster restaurant
4.5
Awesome(4550)
Price: Moderate
• American • Little Italy
Booked 64 times today
Nestled in the heart of San Diego's vibrant Little Italy, Ironside Fish & Oyster is a gem for seafood enthusiasts. Celebrated for its dedication to the freshest and highest quality seafood, this restaurant has transformed a historic auction house into a bustling seafood haven with an expansive raw bar and open-air culinary hubs. Patrons rave about their "10/10 plump oysters" and assert that the "fish and chips may be the best in San Diego." Not to be missed are their lobster rolls, described as "the best thing I ever had!" With its cool vibe and exceptional service, Ironside Fish & Oyster offers an unforgettable dining experience right by the docks where the city's fishing legacy continues to thrive.
A photo of Kettner Exchange restaurant
4.7
Exceptional(1361)
Price: Expensive
• American • Little Italy
Booked 35 times today
Kettner Exchange in Little Italy, San Diego, is a paragon of Contemporary American cuisine, offering a unique dining experience that reflects the very essence of culinary innovation. With its expansive harbor views from the rooftop patio and the culinary prowess of Executive Chef Brian Redzikowski, the restaurant has consistently wowed diners and critics alike, earning a spot on the Michelin Guide's Bib Gourmand list since 2019. Reviews often highlight the inspired menu, such as one diner’s praise for the “magical” way flavors and textures are combined. Another reviewer raves, “UNBELIEVABLE! THE MOST INCREDIBLE DINING EXPERIENCE OF MY LIFE,” underscoring the exceptional quality and creativity on display. Kettner Exchange's commitment to a thrilling gastronomic journey makes it a must-visit for those seeking the best in Contemporary American fare.
A photo of The Henry - Coronado restaurant
4.8
Exceptional(2466)
Price: Moderate
• American • Coronado
Booked 62 times today
The Henry in Coronado is a standout destination for Contemporary American cuisine, capturing the essence of a warm, neighborhood eatery. With its unique blend of industrial and classical decor, The Henry offers an inviting atmosphere that complements its inventive and delicious dishes. Reviewers consistently praise the restaurant, describing it as "one of the best restaurants on Coronado" with "craveable eats and downright delicious cocktails." Favorites like the short rib potstickers, pretzel balls with fondue, and the horseradish potatoes highlight a menu that's both innovative and deeply satisfying. The exceptional service and vibrant ambiance make The Henry a must-visit for anyone seeking a remarkable dining experience in a beautiful setting. Whether it's for a casual brunch or a special dinner, The Henry promises a memorable meal, making it a beloved gem in the Coronado dining scene.
A photo of Cowboy Star restaurant
4.9
Exceptional(4755)
Price: Very Expensive
• American • Downtown
Booked 24 times today
Cowboy Star in the vibrant heart of Downtown San Diego epitomizes the essence of Contemporary American cuisine with a wild-west twist. Celebrated for its dedication to regional heirloom recipes and superior service, Cowboy Star stands out for its use of local, natural, and organic ingredients, ensuring every dish sings with authenticity and freshness. The menu showcases exceptional dishes, such as the Niman Ranch all-natural beef, earning it rave reviews for the "best steak in SD" and a culinary experience that is both genuine and heartwarming. Diners consistently praise the "excellent vibe" and "impeccable service," making it a must-visit for anyone seeking the pinnacle of Contemporary American dining in San Diego.
A photo of CUCINA urbana restaurant
4.7
Exceptional(7105)
Price: Moderate
• American • Banker's Hill
Booked 29 times today
Nestled in the vibrant Bankers Hill neighborhood of San Diego, CUCINA urbana offers a sublime blend of American cuisine with a unique twist. This gem has been delighting patrons since 2009, merging a cozy farmhouse vibe with a modern art installation, making each dining experience both comforting and visually stimulating. The restaurant's dedication to quality is evident, with diners raving about the "stellar" food and "exceptional" service. Highlights include the meatballs with a "spicy" kick and the perfectly cooked rigatoni, not to mention the "spectacular" desserts like tiramisu and limoncello mousse tart. The innovative wine program allows guests to select from a range of both familiar and rare vintages at retail prices, enhancing meals or to enjoy at home. CUCINA urbana isn't just a meal; it's a culinary celebration in the heart of San Diego.
A photo of Great Maple San Diego restaurant
4.8
Exceptional(4386)
Price: Moderate
• American • Hillcrest
Booked 30 times today
Great Maple in San Diego's vibrant Hillcrest neighborhood is celebrated for its exemplary farm-to-table cuisine, crafting a menu that highlights seasonal and local ingredients. Diners rave about the "innovative dishes" and "fresh house-made pies," with special mentions to the "famous maple bacon doughnuts" which are described as an "absolute must-try." The commitment to freshness is palpable, with one reviewer noting, "How do you make veggies that good?" The atmosphere complements the dining experience with its "warm and welcoming ambiance," ensuring every meal is both a delight to the palate and a feast for the senses. Whether it's the "excellent service" or the "social wine list," Great Maple is a beloved destination for those seeking authentic, high-quality farm-to-table dining in San Diego.
A photo of Parc Bistro-Brasserie restaurant
4.8
Exceptional(3121)
Price: Moderate
• American • Banker's Hill
Booked 27 times today
Parc Bistro-Brasserie, nestled in the heart of Bankers Hill, San Diego, is a celebrated haven of French cuisine, meriting its spot on OpenTable’s “100 Best Neighborhood Gems in America for 2021.” Renowned for its seafood-focused approach, the bistro expertly balances classic French dishes with global inspirations. Patrons rave about the "outstanding jumbo shrimp cocktail & steak frites" and the brunch that has been crowned as the "Best Brunch in San Diego." The allure of Parc Bistro-Brasserie is enhanced by its "exceptional food" and ambiance that transforms a meal into a "Paris escape." With glowing reviews like "By far my favorite French restaurant in San Diego! The food is superb!", it's clear that Parc Bistro-Brasserie is a culinary gem that continuously captivates both locals and visitors alike.

How is content generated

See what locals rave about

From verified diners like you
From verified diners like you
  • Kathleen
    Phoenix / Arizona •5 reviews
    5.0
    Dined 1 day ago
    Simply put, one of the best meals I have had the privilege of enjoying! Delightful server, Calvin, was very in tune with the timing of our meal and our needs. The fixed menu was perfect for Christmas Eve, as it kept the meal flowing and decision-making to a minimum. Every course was delectable from the scallop crudo, the creamed mushrooms, and the sea bass, to the date cake with walnut ice cream! Mezcal hibiscus cocktail was creative and tasty, as well! I will definitely be back!
    More info
    Herb & WoodPrice: Expensive• Californian• Little Italy
    4.7
  • Montye
    New Orleans / Louisiana •1 review
    5.0
    Dined 1 day ago
    Food was delicious. Manager was super friendly and even took pics of our family in front of the Christmas tree. Gorgeous views!!
    More info
    Old Town Tequila Factory Restaurant & CantinaPrice: Moderate• Mexican• Old Town
    3.7
  • jim
    San Diego •3 reviews
    5.0
    Dined 2 days ago
    The small plates are entirely original, owing more to Asian and other fusion than to Spanish tapas. The cocktails were original and enhanced the meal. Ambience was great
    More info
    Kettner ExchangePrice: Expensive• Contemporary American• Little Italy
    4.7
  • David
    San Diego •2 reviews
    5.0
    Dined 3 days ago
    We have dined at Ironside a number of times and have not been disappointed. The seafood is fresh the service outstanding and the overall ambience enjoyable. Parking is just around the corner, albeit a little expensive for 2 hours. The wine selection is limited, so if you are looking for a variety of fine wine, you may be disappointed. Overall a great dining experience.
    More info
    Ironside Fish & OysterPrice: Moderate• Seafood• Little Italy
    4.5
  • Donna
    San Diego •14 reviews
    5.0
    Dined on Dec 9, 2024
    We made last minute reservation and enjoyed a quiet lunch. We have always like going to Fred’s as it is a festival environment and fun to be there and hear the music and laughter of others. This time it was quiet due to it being a Monday afternoon and not much going on in the area. The food was very tasty and service great. And it was pleasant and relaxful to enjoy lunch in the unusual quiet environment . DJ
    More info
    Casa De Freds, Tacos y TequilaPrice: Moderate• Mexican• Old Town
    4.5

Discover best American restaurants in Mission Hills

Discover the charm of American cuisine in the delightful neighborhood of Mission Hills, San Diego. This area is celebrated for its eclectic dining scene, where each restaurant brings its unique twist to classic American dishes. Whether you're in the mood for organic, locally sourced meals or innovative farm-to-table experiences, Mission Hills offers a variety of options that cater to your cravings. Patrons consistently praise the area for its high-quality ingredients and the memorable atmospheres provided by these establishments. Reviews often highlight the exceptional service and the creative menus that merge traditional American flavors with modern culinary techniques. As you explore the vibrant dining options in Mission Hills, expect an engaging culinary journey that showcases the best of American gastronomy, making every meal both noticeable and worth the expense.

  • Privacy Policy
  • Terms of Use
  • Cookies and Interest-Based Ads
  • Cookie Preferences
Copyright © 2024 OpenTable, Inc. 1 Montgomery St Ste 500, San Francisco CA 94104 - All rights reserved.
OpenTable is part of Booking Holdings, the world leader in online travel and related services.
Booking Logo
Priceline Logo
KAYAK Logo
Agoda Logo
OpenTable Logo